Phone - 919-668-0820
Bryan Alzheimer's Disease Research Center
2200 West Main Street
Duke University Medical Center
Durham, NC 27705
|Director, Bryan Alzheimer's Disease Research Center|
Professor, Department of Psychiatry and Behavioral Sciences, Division of Medical Psychology
Department of Medicine
Division of Neurology
Dr. Kathleen Welsh-Bohmer is the Director of the Joseph and Kathleen Bryan Alzheimer’s Disease Research Center (Bryan ADRC) at Duke University Medical Center which focuses on basic science discovery and clinical care programs for patients with Alzheimer’s disease and other similar memory complaints. Under Dr. Welsh-Bohmer’s leadership, the Bryan ADRC has established broad collaborative ties locally, nationally and internationally. Among the most important collaborations are those involving statewide community partnerships. Through these community collaborations, the Bryan ADRC is engaged in a number of studies to prevent cognitive disorders and to enhance successful cognitive aging. The work done with First Missionary Baptist Church in Jacksonville NC was recognized for its innovative approach to translate scientific findings into everyday lifestyle changes. This novel partnership was covered by ABC Nightly News with Charlie Gibson and USA today in 2008. Working with Zinfandel and Takeda Pharmaceuticals, the Bryan ADRC will be launching a very large primary prevention study in the year ahead to prevent the onset of memory symptoms in healthy, cognitively normal individuals in the age of risk for AD.
Dr. Welsh-Bohmer’s particular research interests over the past 25 years have been centered on defining the early expression of Alzheimer’s disease and other neurodegenerative dementias with an aim of facilitating disease prevention. She has led large epidemiological studies to examine the prevalence and incidence of late life dementias in relation to avoidable antecedent exposures and other biological determinants. This work has led to a better understanding of how Alzheimer’s disease begins in the brain, tools to recognize the illness very early, and methods for potential prevention. Her current work is focused on using this information gained in these observational studies to advance global trials in preventing Alzheimer’s disease. She has authored over 200 peer-reviewed articles, chapters, and abstracts mostly in the area of Alzheimer’s disease, memory, and aging.
Fellowship, Clinical Neuropsychology, University of Iowa, 1985-87
PhD, Psychology, University of Virginia, 1985
BS, Psychology, Duke University, 1979
Welsh-Bohmer, K.A., Ostbye, T., Sanders, L., et al (2009). Neuropsychological performance in advanced age: Findings from the Cache County Study. Clinical Neuropsychologist, 23(1):77-99.
Roses AD, Lutz MW, Amrine-Madsen H, Saunders AM, Crenshaw DG, Sundseth SS, Huentelman MJ, Welsh-Bohmer KA, and Reiman EM. (2010) A TOMM40 variable length polymorphism predicts the age of late-onset Alzheimer’s disease. The Pharmacogenomics Journal. 10:375-384.
Heinzen EL, Need AC, Hayden KM, Chiba-Falek O, Roses AD, Strittmatter WJ, Burke JR, Hulette CM, Welsh-Bohmer KA, Goldstein DB. (2010) Genome-wide scan of copy number variation in late-onset Alzheimer's disease. J Alzheimers Dis. 19(1):69-77.
Wee, C-Y, Yap, P-T, Zhang, D., Denny, K., Browndyke, J.N., Potter, G.G., Welsh-Bohmer, K.A., Wang, L., & Shen D. (2012). Identification of MCI individuals using structural and functional connectivity networks. Neuroimage. 59(3):2045-56. PMC3008336