Center History
Home About Bryan ADRC

Committed to Clinical Care, Medical Discovery, and Pathways to Prevention and Treatment of Alzheimer's Disease

The Joseph and Kathleen Bryan Alzheimer's Disease Research Center (Bryan ADRC) is a clinical and basic science center dedicated to the highest level of care for patients and families affected by Alzheimer's disease (AD) and other memory disorders, the discovery of the basic mechanisms underlying the disease process, and the development of effective treatments and preventive strategies for AD and related conditions. Established in 1985, the Bryan ADRC is one of the twenty-seven national Alzheimer's Disease Centers (ADC) funded by the National Institute on Aging (NIA). Since its inception over twenty years ago, the Bryan ADRC has led research and delivered state-of-the-art care for people with Alzheimer's disease (AD) and their families. Outpatient specialty services are provided through the Center's Memory Disorders Clinic (MDC).

In addition to its broad portfolio of clinical and basic research activities, the Bryan ADRC offers support services for families caring for persons with memory disorders, community outreach, and education programs.  Information on current scientific and clinical findings is offered to the general public, medical and scientific community via the Bryan ADRC publications, an annual conference, and clinical training programs.

An important emphasis of the Bryan ADRC is to advance basic medical discovery about AD and related dementias. This basic science mission is facilitated through the DNA cell repository located in the Center for Human Genetics (CHG) (previously housed at the Center for Human Genome Variation (CHGV)), and the Bryan ADRC brain donation program of the Kathleen Price Bryan Brain Bank. These affiliated Bryan ADRC programs provide an invaluable source of DNA and fresh brain tissue, which can be sent to laboratories across the globe to hasten research productivity and to generate new ideas through interdisciplinary collaboration.

The Bryan ADRC goals are to improve the diagnosis, care, and treatment for AD patients and to translate genetic and other basic science discoveries into practical treatments and disease prevention. Under the guidance of Dr. Kathleen Welsh-Bohmer, Director, and Dr. James R. Burke, Associate Director, the Bryan ADRC provides an optimal team for AD clinical and basic science studies including faculty from the Departments of Medicine, Psychiatry, Psychology, Pathology, Genetics, Neurobiology, Radiology, and Anesthesiology.

The Bryan ADRC's current research efforts are supported by NIA funds, large and small private gifts from families and supporters, the Alzheimer's Association, and collaborations with pharmaceutical companies here in Research Triangle Park. We thank our many supporters, large and small, and especially our many research participants. The private monetary gifts and the non-monetary gifts of time, effort, and brain donations have played a pivotal role in the advances in Alzheimer's research.

We thank our many supporters, large and small, and especially our many research participants. The private monetary gifts and the non-monetary gifts of time, effort, and brain donations have played a pivotal role in the advances in Alzheimer's research.